Titled Marsh Field House, Mass., this painting by Nesbitt depicts the interior of Isaac Winslow House, Marshfield, Massachusetts, built in 1699. It is the ancestral home of Marshfield's founding family, and was considered an avant-garde South Shore mansion. Still in largely original state, the Isaac Winslow House survives as a great example of how landed gentry lived in pre-Revolutionary America.

Isaac Winslow was a Loyalist doctor who quarantined and inocculated many Marshfield residents who had been infected with smallpox: the grateful community ensured his property was not confiscated after the Revolution. The house also has a place in the history of African-America, being once occupied by manservant Britton Hammon. After voyaging at sea and being captured by Indians off the coast of Florida, Hammon's subsequent escape, and reconciliation with former master John Winslow, resulted in his life story being written. He was therefore amongst the first African-Americans to have work published in the New World.

The house was added to the National Register of Historic Places in 2000.

This painting is one of a series of interiors made by Nesbitt in monochrome in the late 1960s, painted in a large scale.